Nerve injury-induced tactile allodynia is present in the absence of FOS labeling in retrogradely labeled post-synaptic dorsal column neurons

ET Zhang, MH Ossipov, DQ Zhang, J Lai, F Porreca - Pain, 2007 - Elsevier
… in the present investigation that the absence of FOS expression evoked by touch or pinch in
… to express FOS, nor was it an artefact induced by the double-labeling procedures employed. …

Contribution of afferent pathways to nerve injury-induced spontaneous pain and evoked hypersensitivity

T King, C Qu, A Okun, R Mercado, J Ren, T Brion, J Lai… - Pain, 2011 - Elsevier
… expressing neurons blocked SNL-induced thermal and tactiledorsal column projection
can mediate nerve injury-induced … and analyzed to verify absence of preconditioning chamber …

[HTML][HTML] Descending facilitation maintains long-term spontaneous neuropathic pain

R Wang, T King, M De Felice, W Guo, MH Ossipov… - The Journal of …, 2013 - Elsevier
Touch-induced FOS was increased in the spinal dorsal horn … time course of nerve
injury-induced behavioral responses to … touch pathway by physical disruption of the dorsal

The Dorsal Column Nuclei Scale Mechanical Sensitivity in Naive and Neuropathic Pain States

A Upadhyay, MA Gradwell, TJ Vajtay, J Conner… - bioRxiv, 2024 - biorxiv.org
… with neuronal hyperactivity during injury-induced neuropathic … retrograde tracing from the
thalamus to fluorescently label Gr … In summary, we observed an increase in c-Fos+ neurons in …

Differential Activation of Pain Circuitry Neuron Populations in Spinal Cord Injury Induced Neuropathic Pain

EV Brown - 2021 - search.proquest.com
neuronal activation post-SCI, we took advantage of the immediate early gene c-fos, which
is an established marker of neuronal … of mechanical allodynia in peripheral nerve injury, …

Noradrenergic neurons in the locus coeruleus contribute to neuropathic pain

JJ Brightwell, BK Taylor - Neuroscience, 2009 - Elsevier
… of neuronal activity in the LC, we compared the number of Fos-ir … rats in the presence or
absence of sensory stimulation. We … injuryinduced tactile allodynia, but also to cold allodynia

Modulation of sensory processing by direct descending projections from the somatosensory cortex to the spinal dorsal horn

N Frezel - 2019 - theses.hal.science
injury-induced mechanical hypersensitivity15. Activation of the … In mice for example, the
immediate early gene c-fos is upregulated … Using rAAV vector based retrograde tracing, we have …

[PDF][PDF] Spinal cord retinoic acid receptor signaling gates mechanical hypersensitivity in neuropathic pain

B Cao, G Scherrer, L Chen - Neuron, 2022 - cell.com
… -injuryinduced homeostatic changes that lead to central … retrograde labeling of dorsal horn
nociceptive projection … idence that concomitant pre- and post-synaptic disinhibition of the iPV+ …

Genotype-selective phenotypic switch in primary afferent neurons contributes to neuropathic pain

A Nitzan-Luques, M Devor, M Tal - PAIN®, 2011 - Elsevier
… Spinal nerve injury induced a decrease in the proportion … , using retrograde labeling from
the GN, that such neurons do … with tactile allodynia, the dorsal horn neurons that express Fos

Neurochemical characterization of neuronal populations expressing protein kinase C gamma isoform in the spinal cord and gracile nucleus of the rat

AS Hughes, S Averill, VR King, C Molander… - Neuroscience, 2008 - Elsevier
… of PKCγ cells in the dorsal column nuclei of the adult rat. Retrograde labeling of PKCγ cells
from … of c-fos reflects monosynaptic activation of post-synaptic neurons by nociceptors by 2 h …